Single-cell Pediatric Cancer Atlas

Single-Cell Pediatric Cancer Atlas (ScPCA)

Accelerating the discovery of better treatments for pediatric solid tumors and leukemias

Single-cell profiling is an exciting technology that can provide insight into how certain cells influence cancer progression and treatment response.

ALSF funds cutting-edge pediatric cancer research

Alex’s Lemonade Stand Foundation (ALSF) funded 10 awards for childhood cancer investigators from 8 different institutions working on single-cell profiling to create a publicly available atlas of single-cell pediatric cancer data.

The Data Lab processes the generated data

The Data Lab processes the single-cell, single-nuclei, and bulk RNA sequencing data generated by the ALSF-funded researchers. The data from these patient tumors is made widely and easily available in one location through the ScPCA Portal.

Take me to the ScPCA Portal

ScPCA Portal currently has

Cancer Types

532

Total Samples

Projects

Labs

You can view the number of tumor types and samples being processed here.

Impact

Open Source
and Free

The portal makes research faster and more cost-effective by uniformly processing the data with an open source, freely available, and well documented pipeline.

Trustworthy and Reproducible

The open source pipeline cultivates trust in the data and allows researchers to immediately utilize it for their own analyses and ensures reproducible results.

Making cutting-edge technology more accessible

Single-cell RNA sequencing is a cutting-edge technology and may not be available to all childhood cancer experts. The portal makes the outputs of this project widely accessible.

Take me to the ScPCA Portal

Contribute data to the ScPCA Portal

We accept submissions from pediatric cancer researchers with existing single-cell datasets! Eligible datasets will be made publicly available on the portal, enhancing the visibility of your work and making your research more discoverable by others. Researchers must process datasets using the Data Lab’s production pipeline to maintain consistency with other projects, submit the data, and sign a Data Transfer Agreement. Eligible researchers may receive a small one-time grant for their submission. View the full guidelines to learn more.

If you are interested in being a part of the ScPCA, the Data Lab is here to support you throughout the submission process. To get started, complete the intake form and the Data Lab will contact you within 3 business days to notify you of your eligibility and provide additional information required for submission.

Complete the intake form